BDBM50122002 CHEMBL1383671

SMILES Nc1cnccc1C(O)=O

InChI Key InChIKey=FYEQKMAVRYRMBL-UHFFFAOYSA-N

Data  14 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50122002   

TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  631nMAssay Description:Inhibition of KDM4C (unknown origin) using H3K9Me3 peptide as substrate assessed as demethylation of substrate by Rapidfire mass spectrometric analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  631nMAssay Description:Inhibition of KDM4C (unknown origin) measured by RapidFire mass spectrometry (RFMS)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLysine-specific demethylase 4C(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50122002(CHEMBL1383671)
Affinity DataIC50:  631nMAssay Description:Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed